Protein Labeling Reagents
Cayman Chemical C6 BIotIn dIhydro CRamIDd 5mg
An affinity probe for C6 dihydro ceramide binding partners
Santa Cruz Biotechnology FP-Biotin (CAS 259270-28-5) 1mg Purity: ≥98% Molecular Weight: 592.75Molecular Formula:C27H50FN4O5PS
FP-Biotin is a biotinylated organophosphorus agent that may be useful in identifying proteins that react with organophosphorus toxicants (OP). It is a small molecule that is composed of a biotin molecule attached to a fluorescent dye, fluorescein. FP-biotin has a wide range of applications in scientific research, as it can be used for labeling, imaging, and detection of molecules. It is also used in a variety of laboratory experiments, such as protein purification, enzyme assays, and DNA sequencing. Common techniques it is used in are western blotting, ELISA, and affinity chromatography.
AdipoGen Biotin Sulfone
Chemical. CAS 40720-05-6. Formula C10H16N2O5S. Molecular Weight 276.31. Biotin sulfone is an oxidized form of biotin and is as efficient as biotin in streptavidin binding and it binds to avidin with a binding ratio of 0.332 compared with biotin. Biotinylated synthetic oligosaccharides are an attractive tool, as streptavidin coated plates and beads are commercially available and widely use in serological assays. As biotin is chemically reactive, and not compatible with carbohydrate protecting group manipulation, the use of biotin sulfone tagged oligomannosides BSTO for antigen immobilization in candidiasis or allergy diagnosis has been used. The use of biotin sulfone also offers a convenient solution for both oligosaccharide synthesis and immobilization on microspheres and surface plasmon resonance sensors.
Medchemexpress LLC FAM azide, 6-isomer | 1386385-76-7 | MFCD29912889 | 99.8% | 10 MG
FAM azide, 6-isomer is a fluorescein-derived azide labeling reagent used for fluorescent tagging and bioconjugation via click chemistry. It offers a bright fluorescein signal and an azide functional group for efficient conjugation to alkyne-containing molecules.
- Fluorescent fluorescein-based dye with azide functional group.
- Compatible with copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Compatible with strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO/BCN reagents.
- Supplied as a solid; solution variants in DMSO are also available from some suppliers.
- Molecular weight 458.42 and CAS 1386385-76-7; high purity for labeling applications.
- Available in small pack sizes suitable for research-scale labeling.
Apexbio Technology LLC Sulfo-NHS-LC-D-Desthiobiotin 1mg
Sulfo-NHS-LC-D-Desthiobiotin is a sulfonated amine-reactive labeling reagent targeting primary amines on proteins or peptides It is designed to covalently label cell-surface proteins by reacting with lysine residues or protein N-termini thereby enabling selective modification of these proteins Sulfo-NHS-LC-D-Desthiobiotin exerts its biological activity primarily through covalent reaction with primary amines via its activated Sulfo-NHS ester Due to its membrane-impermeable negatively charged sulfonate group it selectively labels cell-surface proteins without entering intact cells Based on these chemical properties Sulfo-NHS-LC-D-Desthiobiotin holds research potential in affinity purification biotin-streptavidin interaction assays selective enrichment and analytical workflows involving reversible labeling of surface proteins
Medchemexpress LLC Desthiobiotin-Iodoacetamide | 2924824-04-2 | C14H25IN4O3 | 50 MG
Desthiobiotin-Iodoacetamide serves as an ADC linker, a crucial component in antibody-drug conjugates. This compound can function as a probe to label cell lysis treated with Oridonin. It is supplied as a white to off-white solid with a high purity of 99.51%.
- Functions as an ADC linker
- Can be used as a probe for Oridonin-treated cell lysis
- Relevant for research in cancer, targeted therapy, and immunotherapy
- Solid appearance, white to off-white
- Purity of 99.51%
Medchemexpress LLC Desthiobiotin-NHS ester | 80750-24-9 | MFCD08062086 | >98.0% | 311.33 | C14H21N3O5 | 1 G
Desthiobiotin-NHS ester is an NHS-activated desthiobiotin reagent that reacts with primary amines to form stable amide bonds, enabling reversible affinity capture with streptavidin in labeling and bioconjugation workflows. Supplied as a dry powder with recommended low-temperature storage, it is used for protein labeling, biochemical assays, and metalloprotein probing.
- Reacts with primary amines to form stable amide bonds.
- Enables reversible streptavidin-based capture due to lower affinity than biotin.
- Suitable for protein labeling, bioconjugation, and biochemical assays.
- Supplied as a powder with recommended low-temperature storage.
- High purity for reliable conjugation performance.
Medchemexpress LLC Desthiobiotin-PEG4-acid | >98% | 461.55 | 25 MG
Desthiobiotin-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used as a PEG-based PROTAC linker
- Useful in the synthesis of PROTACs
- Enables selective degradation of target proteins
Medchemexpress LLC Desthiobiotin polyethyleneoxide iodoacetamide | 97.7% | C21H38IN5O6 | 100 MG
Desthiobiotin polyethyleneoxide iodoacetamide is a compound useful for cysteine labeling in chemoproteomic experiments. It is for research use only and not sold to patients.
- Useful for cysteine labeling in chemoproteomic experiments
- Available in solid form
- White to light yellow in color
- Molecular weight of 583.46
- Store powder at -20°C for 3 years
- Unstable in solutions, freshly prepared solutions recommended
Medchemexpress LLC Sulfo-nhs-lc-biotin sodium | 191671-46-2 | 98.0% | 50 MG
Sulfo-NHS-LC-Biotin sodium is an amine-reactive ester derivative of biotin that cannot cross the intact blood-retinal barrier. It is utilized to assess the vascular permeability of both the brain and retinal vasculature. The product is for research use only.
- Reacts with amines to form a stable bond.
- Does not pass the blood-retinal barrier.
- Can be used to evaluate permeability in the brain and retinal blood vessels.
- Available in solid form.
- White to yellow in color.
- Stable at room temperature for shipping.
- Store at 4°C, sealed, and away from moisture.
Apexbio Technology LLC Sulfo-NHS-SS-11-Biotin,100mg
Sulfo-NHS-SS-11-biotin is a long-chain cleavable amine-reactive biotinylation reagent. The presence of the negatively charged sulfonate group in the chemical structure of sulfo-NHS-SS-11-biotin makes it a water-soluble biotinylation reagent that can be directly added to aqueous reactions without prior dissolution of organic solvents. Although no prior dissolution is required, an aqueous stock solution of sulfo-NHS-SS-11-biotin must be prepared rapidly and used immediately in case of the occurrence of hydrolysis of the active ester. Sulfo-NHS-SS-11-biotin has been used to react with amine-containing proteins and other molecules forming a complex which further interacts with avidin or streptavidin probes and to purify targeted molecules using affinity chromatography on a column of immobilized avidin or streptavidin. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC Biotin-HPDP | 129179-83-5 | MFCD00078541 | 99.7% | 539.78 g/mol | C24H37N5O3S3 | 5 MG
Biotin-HPDP is a sulfhydryl-reactive biotinylation reagent used to label and affinity-purify cysteine-containing proteins. It forms a reversible disulfide linkage to thiol groups, enabling reversible labeling and recovery of native proteins. The compound has a molecular weight of 539.78 g/mol and a reported purity of 99.73%.
- Sulfhydryl-reactive biotinylation reagent that targets free thiols.
- Forms reversible disulfide linkage enabling recovery of native proteins.
- Suitable for labeling and affinity purification of cysteine-containing proteins.
- High reported purity for reproducible experimental results.
- Soluble in DMSO and compatible with common in vivo formulations.
- Available in small research sizes for laboratory use.
Dojindo Molecular Technologies Inc -SulfoBiotics- Biotin-HPDP(WS) solution (500 μL) is a novel water-soluble biotin-labeling reagent that is modified from Biotin-HPDP, easy-to-use aqueous solution including 20 mmol/l Biotin-HPDP(WS).
Biotin-HPDP is a reagent widely used to introduce a biotin moiety to a sulfhydryl group of protein via a reversible disulfide bond via the Biotin switch method. This reagent is useful for affinity-purification of biotinylated proteins by using avidin-coated beads, because the disulfide bond can be cleaved by a reducing agent. However Biotin-HPDP has very low solubility in a solvent, and it is necessary to dissolve it by using an organic solvent such as DMSO or DMF. The preparation of this solution is time-consuming.Biotin-HPDP(WS) solution is a novel water-soluble biotin-labeling reagent that overcomes the problems of Biotin-HPDP by dramatically improving its solubility in water. Moreover, since it is a 20 mmol/L aqueous solution, no reagent dissolution operation is required. Dojindo offers various sulfur biology reagents. (https://www.dojindo.com/sulfur-biology/)